![]() Golden retrievers in the US show significantly elevated lifetime risk for both B-cell lymphoma (6%) and hemangiosarcoma (20%). Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically similar to human B-cell non-Hodgkin lymphoma and angiosarcoma, respectively. Azuma, Chiekoĭogs, with their breed-determined limited genetic background, are great models of human disease including cancer. ![]() Kim, Jong-Hyuk Barber, Lisa Burgess, Kristine Lander, Eric S. Ito, Daisuke Mauceli, Evan Arendt, Maja Noh, Hyun Ji Koltookian, Michele Biagi, Tara Fryc, Sarah Williams, Christina Avery, Anne C. Tonomura, Noriko Elvers, Ingegerd Thomas, Rachael Megquier, Kate Turner-Maier, Jason Howald, Cedric Sarver, Aaron L. Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers The results suggest that sharing office space increases the risk of the common cold, although the primary mode of transmission-airborne, direct or indirect contact-remains controversial. Females (OR 1.25, 0.95-1.66) and all under 40 years of age (OR 1.15, 0.86-1.55) had non-significantly increased risk, while smokers did not differ essentially from non-smokers (OR 1.05, 0.76-1.42). Among all workers higher risk also emerged for those with young children (OR 1.46, 1.05-2.04) or a history of hay fever (OR 2.07, 1.47-2.92). In logistic regression analysis the adjusted odds ratio (OR) for more than two episodes of common cold during the past 12 months in subjects with one or more office colleagues vs those working alone was 1.35 (95% CI 1.00-1.82). The study population, one person from each office on floors 3 to 8, consisted of 893 workers, 493 males (49.2%) and 454 females (50.8%). Data on respiratory infections and the relevant personal and environmental determinants were collected in a self-administered questionnaire (response rate 71.0%). ![]() The effect of sharing an office with one or more colleagues on the risk of the common cold was studied in a modern, mechanically ventilated, 8 story office building in central Helsinki. Despite its long-established ubiquity, little is yet certain about the determinants of indoor environment in spreading of the infection, and even less about the role of indoor air quality as a mediator. The common cold persists as a major economic and public health problem worldwide. Shared office space and the risk of the common cold. ![]()
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